2021 Experiential Internship, Mass Spectrometrist
The small molecules mass spectrometry team within the predictive stability and structural elucidation group supports the identification of low-level unknown compounds in development pipeline. The team utilizes high resolution accurate-mass mass spectrometry to elucidate chemical structures and solve complex scientific questions related to molecules of pharmaceutical interest. The goal of this internship is to evaluate the potential application of gas phase ion/molecule reactions to characterize potentially mutagenic impurities in process development. The intern will explore innovative scientific approaches to support the development of mass spectrometry techniques to characterize potentially mutagenic compounds. Additionally, the intern will utilize computational approaches to understand the gas phase fragmentation mechanism of unknowns in development pipeline.
Qualifications
Preferred Qualifications:
- Solid understanding of the principles and applications of mass spectrometry
- Experience with molecular modeling and molecular dynamics simulations
- Fundamental understanding of organic chemistry
- Ability to read and understand the literature and formulate hypothesis and ideas
- Ability to independently design and execute experiments
- Routinely shows scientific curiosity and explore new ways of doing things
Minimum Qualifications:
- Minimum GPA = 3.0/4.0
- Returning to university for at least one semester
- Currently enrolled in university, pursuing a PhD in Biochemistry, Chemistry, or a related field
- Demonstrated leadership skills (i.e. extracurricular activities or projects)
- Must be authorized to work in the US on a permanent basis without requiring sponsorship